Johns Hopkins Medicine-Led Team Develops Fluid Biomarker for Early Detection of ...

Retrieved on: 2024-03-18 18:59:44

Tags for this article:

Cognitive disorders

Rare diseases

Dementia

Frontal lobe

Frontotemporal dementia

Temporal lobe

ALS

TAR DNA-binding protein 43

C9orf72

Genetics of amyotrophic lateral sclerosis

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Johns Hopkins Medicine-Led Team Develops Fluid Biomarker for Early Detection of .... View article details on HISWAI: https://www.hopkinsmedicine.org/news/newsroom/news-releases/2024/03/johns-hopkins-medicine-led-team-develops-fluid-biomarker-for-early-detection-of-degenerative-diseases-als-and-ftd

Summary

The article discusses how Johns Hopkins Medicine researchers are identifying early biomarkers for ALS and FTD, focusing on a cryptic exon-linked protein (HDGFL2) that correlates with TDP-43 function loss and could aid in early detection. Additionally, the study explores genetic links to these cognitive disorders by examining patients with C9orf72 mutations.

Article found on: www.hopkinsmedicine.org

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