Keep your enemies closer: targeting membrane-proximal domains for improved immunotherapy

Retrieved on: 2021-03-15 19:41:15

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Clinical medicine

Chimeric antigen receptor T cell

CD33

Monoclonal antibody

Antibody

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Keep your enemies closer: targeting membrane-proximal domains for improved immunotherapy. View article details on HISWAI: https://www.fredhutch.org/en/news/spotlight/2021/03/crd-godwin-leukemia.html

Excerpt

For example, antibody-based immunotherapies targeting the leukemia antigens ... For instance, antibodies that bind and alter the functionality of surface ... raised their own C2-set-targeting monoclonal antibody by immunizing mice ...

Article found on: www.fredhutch.org

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