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Structural analysis of the PTEN:P-Rex2 signaling complex reveals how cancer-associated ...

Retrieved on: 2021-05-04 18:00:00

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Structural analysis of the PTEN:P-Rex2 signaling complex reveals how cancer-associated .... View article details on HISWAI: https://stke.sciencemag.org/content/14/681/eabc4078

Excerpt

These data suggest that PTEN binds to P-Rex2 by bridging both the P-Rex2 PDZ domain 2 and IP4P domains. PTEN binding blocks the Gβγ-mediated ...

Article found on: stke.sciencemag.org

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