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One-carbon-mediated purine synthesis underlies temozolomide resistance in glioblastoma

Retrieved on: 2024-10-25 23:08:24

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One-carbon-mediated purine synthesis underlies temozolomide resistance in glioblastoma. View article details on hiswai:

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... protein (MTHFD2/L) [11, 12]. De novo purine synthesis is a 10-step cytosolic reaction that results in the production of inosine monophosphate (IMP).

Article found on: www.nature.com

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